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Patient characteristics are provided in Table 2 and Supplementary Tables S1 and S2

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The effects include addiction, priming for use of other addictive substances, reduced impulse control, deficits in attention and cognition, and mood disorders. According to a 2012 study by Goriounova and Mansvelder, the prefrontal cortex (PFC), the brain area responsible for executive functions and attention performance, is one of the last brain areas to mature and is still developing during adolescence