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The English who followed also raised tobacco, using it to pay taxes and land rents to William Penn, and exporting it

Encourage patients who are motivated to quit and who did not succeed in stopping smoking during prior CHANTIX therapy for reasons other than intolerability due to adverse events, or who relapsed after treatment to make another attempt with CHANTIX once factors contributing to the failed attempt have been identified and addressed [see Dosage and Administration (2.1), Clinical Studies (14.6)]

This does not make smokeless tobacco safe, however

Many smokers now explore different blends based on nicotine strength, session type, and personal preference