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The Food and Drug Administration also upped its scrutiny of a number of key aspects of Juuls business, telling the company to turn over documents on its marketing, educational programs and nicotine formula

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Primack and James Sargent, a professor of pediatrics at Dartmouths Geisel School of Medicine, theorized that their appeal stems in part from the fruity flavors of e-cigarette liquids and television commercials, some of which feature Hollywood actors

Nearly 700 new psychoactive substances have been identified globally in the past decade