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Genes play a significant role in the transition from problematic use of substances of abuse to developing an addiction, according to a 2012 article by Francesca Ducci and David Goldman published in the journal Psychiatric Clinics of North America , titled The Genetic Basis of Addictive Disorders . The genetic makeup of an individual contributes to the development of addiction by influencing how the brains reward circuitry works, interacting with environmental factors to increase vulnerability, and increasing the risk of developing a psychiatric condition or disorder that in turn, raises the likelihood of developing an addiction

As a countermeasure, they were taking steroids

Unlike varenicline, though, the exact process by which bupropion works to facilitate smoking cessation is yet unclear

I have one worse (6) but what is your pick