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Consumers shift to reduced-risk products Nicotine pouch volumes are expected to grow by 21 percent annually in the coming decade, while cigarettes will fall by nearly 8 percent

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A vein bypass first versus a best endovascular treatment first revascularisation strategy for patients with chronic limb threatening ischaemia who required an infra-popliteal, with or without an additional more proximal infra-inguinal revascularisation procedure to restore limb perfusion (BASIL-2): an open-label, randomised, multicentre, phase 3 trial