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They need to determine whether the Philip Morris evidence supports the marketing claims the company would like to make about IQOS, which include: IQOS significantly reduces the production of harmful and potentially harmful chemicals. Switching completely to IQOS presents less risk of harm than continuing to smoke cigarettes. Scientific studies have shown that switching completely from cigarettes to the IQOS system significantly reduces your bodys exposure to harmful or potentially harmful chemicals. Philip Morris also has a separate application, making its way through the FDA, to simply sell the product in the US

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It has been proposed that the THR potential, when considering the ability of novel nicotine and tobacco products to reduce harms among adult current smokers, is optimal when appeal and dependence potential (abuse liability) are high and when and toxicity/harmfulness are low 7