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Hence, it is plausible that the MOE for alcohol can be lower than the one for heroin, purely because of the high exposure to alcohol in the European society (see also Rehm et al

Nicotine is a very powerful stimulant and it prevents a good nights sleep by: Increasing the heart rate Causing a rise in blood pressure Triggering adrenaline production Disrupting the circadian rhythm Impacting REM (dreaming) sleep and causing wakefulness due to nicotine withdrawal Vaping also negatively affects sleep due to its influence on snoring and sleep apnoea