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Substance misuse can affect different aspects of your life and can cause any or all of the following: A range of health problems like heart disease, liver damage, and respiratory infections Mental health issues like anxiety, depression, and psychosis Long-term impairment of cognitive functions such as memory, attention, and decision-making Risky behaviors including engaging in criminal activity Social isolation and loss of support system Financial instability possibly caused by loss of employment due to poor job performance A range of legal issues including arrests and incarceration A clearer understanding of the risks of using addictive sentences can hopefully help people steer clear of them