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E-cigs are not required to be subjected to product safety testing, according to the U.S

Methods Design This study primarily adapted the research design and protocol of the Tobacco Pack Surveillance System (TPackSS) and its 2015 Field Collection Protocol developed by the Institute for Global Tobacco Control (IGTC) at the Johns Hopkins Bloomberg School of Public Health [36]

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Although tobacco use in the form of cigarette smoking is declining in countries such as the USA, many other countries are experiencing an increase in tobacco use, especially within the poorer countries