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When the heterogeneity between studies is not considered (reflecting a traditional meta-analytic approach), chewing tobacco users were found to have a 2.14 (1.772.57)-fold increased risk of esophageal cancer (Table 2

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It is responsible for the whole process of introducing new tobacco products to the market, starting with the necessary research and completing it with giving the needed authorization, such as permit to circulate as a tobacco product or permit to circulate as a tobacco product of reduced harm

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