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Ever since the 1970s, an increase in rate (market by yellow) creates a short spike in revenue followed by a steep drop-off in revenue

Nat Mater (2015) 14:9634.10.1038/nmat4432 Summary Keywords cigarette smoking, gastrointestinal inflammation, inflammatory bowel disease, ulcerative colitis, Crohns disease Citation Berkowitz L, Schultz BM, Salazar GA, Pardo-Roa C, Sebastin VP, lvarez-Lobos MM and Bueno SM (2018) Impact of Cigarette Smoking on the Gastrointestinal Tract Inflammation: Opposing Effects in Crohns Disease and Ulcerative Colitis

Additionally, cessation rates in patients with SZ remain significantly lower than those of the general population, and it is evident that a more holistic treatment strategy is required (164)

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