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And while the death toll from smoking may be its most striking legacy, the study of smoking also reveals aspects of social, cultural, economic and political history, all areas that I explore in my monograph on the history of smoking in Italy in the nineteenth and twentieth centuries.[i] In what follows I present some of the available smoking statistics in post-World War II Italy and close with an observation on mortality

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[24] Smoking history is a crucial factor in the severity of APESCGIT

moreover, treatment with alpha-tocopherol and n-acetylcysteine, which have recognised anti-oxidant properties, provided a partial rescue of these cells, thus suggesting the involvement of reactive oxygen species in this pathological cascade.80 The potential interference with thrombosis and inflammation mechanisms was suggested by another study showing that exposing platelets to electronic cigarette vapour extracts induced a significant upregulation of the pro-inflammatory complementary elements C1 and C3b, even higher than traditional tobacco smoke extracts, and was accompanied with a concomitant boost in platelet activation, aggregation and adhesion capacity