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And then COVID came along and changed how many of us work, resulting in one of the biggest shifts in travel patterns since it started being measured: working at home jumping from 12% to 18%

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These individual variations in nicotine tolerance are at least in part due to the pharmacogenetics of Cytochrome P450 2A6 (CYP2A6), the hepatic enzyme primarily responsible for nicotine metabolism [18]

"But we need independent evidence to support any claims made by the tobacco industry." ASH said that until independent evidence shows that IQOS and similar products are substantially less harmful than smoking, they should be regulated in the same way as cigarettes