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Despite the fact that the smoker and non-smoker asthma patients had similar numbers of circulating neutrophils, circulating neutrophils correlated positively with smoking amount (PY) (Supplementary Fig

Later, an investigation of other workers at the same factory (who didn't have BO but had higher-than-average rates of other breathing issues) concluded that there was a link between the extent of the workers' airway damage and their exposure to diacetyl, a chemical used in artificial butter flavoring

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Subsequent analyses used the refined two-factor solution