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3 Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, USA Background: Viral infections are considered a major driving factor of chronic obstructive pulmonary disease (COPD) exacerbations and thus contribute to disease morbidity and mortality

This condition causes severe dehydration, nausea and vomiting, and some people need to seek medical attention for it

In this review, we comprehensively describe and discuss the impact of acetaldehyde, acrolein, and formaldehyde on mitochondrial function and content and the molecular pathways controlling this (biogenesis versus mitophagy) in epithelial cells of the airways and lungs