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Minimum Legal Sales Age (MLSA): Strictly 21, with a Generational Shift Aligning with federal Tobacco 21 legislation, the minimum age to purchase, possess, or be given any tobacco product, including all e-cigarettes and vapor products, in Massachusetts is 21 years old
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A peer-reviewed review published in PMC specifically named corticosteroids such as prednisolone as drugs metabolized by CYP3A and warned that CBD, as a potent inhibitor of that pathway, may decrease glucocorticoid clearance and increase the risk of steroid-related side effects
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