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Finally, (i) the sensitivity of PG and GLY to thermal oxidation, (ii) the catalysis of their dehydration reactions by acids and/or metals, and (iii) the variability in the heat transfer efficiencies of individual clearomizers and heating coils should be taken into account when considering strategies to minimize toxin production and inter-laboratory inconsistencies in evaluating these devices

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Moreover, it is imperative to start tobacco control programs in order to limit and/or prevent tobacco smoking 30,37