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Chronic nicotine use dysregulates this system, increasing stress sensitivity and emotional instability over time. Additionally, Mendelian randomization studies have found causal evidence that smoking increases the risk of developing depression and even schizophrenia, rather than simply being a consequence of them. This supports the view that smoking may not only sustain but also exacerbate or even initiate mood disorders in vulnerable individuals

More than 10 times as many U.S

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Alongside genealogy, the Guinness World Records believe there may have been another factor in Jeannes long life and tranquil state of mind