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The updated Cochrane review on nicotine receptor partial agonists (varenicline and cytisine) for smoking cessation found that, in studies directly comparing cytisine and varenicline, there may be no difference from either medication for quitting smoking

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And when the smoker lights up, chemical reactions in the burning leaves fill the smoke with carbon monoxide, hydrogen cyanide and a cocktail of carcinogens the infamous polycyclic aromatic hydrocarbons (PAHs), and vapour-borne volatiles like formaldehyde and benzene

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