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This depletion is compounded by topping and de-suckering plants, which increase the nicotine content and leaf yields of tobacco plants

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Although smoking cessation may reduce the risk of rapid progression of AAA, it still exerts a lasting effect on the development and operation of AAA, and the condition is more likely to occur in smokers than non-smokers

any electronic smoking device, and any substances that may be aerosolized or vaporized by such device, whether or not the substance contains nicotine