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Specifically, one study highlighted that patients treated with the naltrexone-bupropion combination who were also taking metformin experienced nausea more frequently (46.2%) compared to those not on metformin (28.2%) (Hollander et al., 2013)

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[6] [10] When asked by Rose whether he had reminded the RADA of this, Oldman joked that "the work speaks for itself"