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Also, overexpression of heme oxygenase-1, a stress-induced enzyme that produces endogenous carbon monoxide, has been found to protect dopaminergic neurons from neurotoxicity in an animal model of Parkinsons. In addition, nicotine, a major constituent of cigarette smoke, has been found to be ineffective at slowing the diseases progression in a recently reported clinical trial
However, the benefits in other areas more than made up for any problems related to weight gain, so we recommend that doctors advise patients to quit while offering nutrition counseling that might minimize the weight gain. The study, which appears in Hypertension , analyzed pregnancy records from more than 22 million pregnancies to compare outcomes among smokers, nonsmokers and those who quit smoking early in pregnancy
