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Practical Takeaways Recognize smoking cessation as a critical intervention for GERD management Understand that smoking affects multiple anti-reflux mechanisms simultaneously Expect that GERD symptoms may improve significantly after smoking cessation Consider that nicotine replacement therapy may continue to affect sphincter function Be aware that smoking even small amounts can impair reflux defense mechanisms Counsel patients that smoking cessation benefits extend beyond general health to specific GERD improvement Related Studies and Research Walking and Chewing Reduce Postprandial Acid Reflux Global Prevalence and Risk Factors of Gastroesophageal Reflux Disease Current Advancement on the Dynamic Mechanism of Gastroesophageal Reflux Disease ACG Clinical Guideline: Guidelines for the Diagnosis and Management of Gastroesophageal Reflux Disease Episode 25: The Great GERD Mistake - How Medicine Made Heartburn Worse and How to Fix It FAQs How quickly do GERD symptoms improve after quitting smoking

doi:10.1056/NEJMsr031421

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