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Similarly, another study in rats demonstrated that inhibition of P-gp, MRP1 and BCRP caused a direct retention of radiolabelled substrates in epithelial cells, increasing substrate exposure (Mairinger et al

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Research on NRT suggests that nicotine gum can be effective in preventing lapses if persons who formerly smoked, or occasionally do, could be encouraged to consume it more often when faced with cravings to smoke [45]

It lets you understand how they might affect your calorie intake