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As Gary Cross and Robert Proctor explain, the shift from air-cured to flue-cured tobacco was something like the shift from opium to heroin or from eating to injecting drugs by means of a hypodermic needle: a new form of consumption based on a new and intensified form of packaged delivery. It was curiously in being made more mild that tobacco became lethal
Nicotine is an addictive substance naturally found in some plants, such as tobacco
Neurology, 87 (17), 17701776
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