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The model simulates yearly outcomes through a series of probabilities of changing tobacco use behaviours and corresponding health risks, societal medical costs and productivity losses as summarised below with additional detail provided in online supplement 1

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It may also become hard and brittle, so meaning that the leaves break under the slightest mechanical stress and eventually end up as powder

Menthol and other flavours will be banned from 2022, but in a blow to the UK government MEPs decided on Tuesday that most electronic cigarettes, increasingly popular as alternatives to tobacco products, need not be regulated in the same way as medicines