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WS-3 and WS-23 are extremely popular because they reduce inhalation harshness and make the throat hit smoother. The researchers exposed rats to aerosols from e-cigarettes with and without cooling additives and examined how the presence of these compounds affected heart rhythm

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Importantly, we used scRNA-seq to deconstruct smoking effects on the epithelium to the cell-type level, which we have then reassembled into a comprehensive model of how smoking modifies epithelial function as a whole (Fig