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For evaluation of varenicline as a pharmacotherapy option for smoking cessation in smokers with mental illness, 15 articles (13 RCTs) were selected from a previous systematic review and updated evidence and included for data synthesis.16, 17, 21, 30, 36, 40, 44, 51, 55, 56, 470, 471, 472, 473, 474 The results indicated that varenicline was significantly more effective than placebo in achieving smoking cessation at six months or longer (RR, 2.17

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From potent sips to lung-busting rips, the Lobo is designed for light users who just want to dip their toes in a bit, heavy users who want the fullest extraction, and everyone in between