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10.12659/msm.942507 Summary Keywords environmental tobacco smoke (ETS), nicotine, oxidative stress, e-cigarettes, DNA damage/repair Citation Kisby G and Raber J (2025) World no-tobacco: effects of second-hand smoke (SHS) and vapors on the developing and adult brain

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Propylene glycol is widely regarded as safe for human use when consumed in moderate amounts .Propylene glycol has very low acute oral toxicity, meaning it takes a large amount to produce noticeable health effects in humans.Toxicity from propylene glycol typically occurs only at plasma concentrations above 4 g/L , which requires an exceptionally high intake within a short period