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A study published in 2015 in the Journal Environmental Health Perspectives showed that harmful chemicals associated with "popcorn lung" are present in many types of flavored e-cigarettes, particularly those with flavors like fruit and candy that may appeal to young smokers

The nature of vaping itself presents dangers, but inhaling fentanyl through vaping devices allows chemicals to enter the bloodstream more quickly, leading to a rapid onset of effects

The first review was an overview of Cochrane reviews on the benefits and harms of behavioural, pharmacologic, and other (e.g., acupuncture) therapies.22 We conducted an overview of Cochrane reviews because there were existing Cochrane reviews of all interventions that would likely be considered and these reviews transparently report assessments of risk of bias and other elements important for assessing evidence certainty

[5] It was introduced to Sulawesi and the Maluku Islands