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[93] Other manifestations [edit] Hiatal hernia [52] Gastroesophageal reflux [94] Poor gastrointestinal motility [95] Dysautonomia [96] Gorlin's sign (touch tongue to nose) [97] Anal prolapse [52] Flat feet Tracheobronchomalacia / tracheal collapse Collapsed lung (spontaneous pneumothorax) [40] Nerve disorders (carpal tunnel syndrome, acroparesthesia, neuropathy, including small fiber neuropathy) [98] Insensitivity to local anesthetics [99] Dental problems including gum disease and enamel hypoplasia Platelet aggregation failure (platelets do not clump together properly) [100] Mast cell disorders (including mast cell activation syndrome and mastocytosis) [101] Pregnancy complications: increased pain, mild to moderate peripartum bleeding, cervical insufficiency, uterine tearing, [42] or premature rupture of membranes [102] Hearing loss may occur in some types [103] There is some evidence that EDS is associated with greater than expected frequencies of neurodevelopmental disorders such as attention deficit hyperactivity disorder (ADHD) and other learning, communication and motor issues, including autism spectrum conditions and Tourette syndrome

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Recurring infections

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