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In January 2026, Philip Morris International presented to the FDA's Tobacco Products Scientific Advisory Committee, advocating for a claim that switching entirely to ZYN could lower the risk of six smoking-related diseases

Atherosclerosis is a condition in which plaque builds up in the arteries, which is also known as hardening of the arteries

"Most research has been conducted in cohorts with too few individuals thus lacking statistical power to uncover the rarer associations," he said

Heart disease refers to a range of conditions that involve the heart, including coronary artery disease, heart failure, arrhythmia, and heart valve problems