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Moreover, at least the lungs, kidneys, and brain emerge as body parts that may be partially involved in nicotine metabolism

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These findings support the interpretation that the lower odds of hypertension observed in our study among exclusive e-cigarette users, who were overwhelmingly former smokers, may partly reflect the removal of combustible tobacco exposure, though the contribution of healthy switcher bias and residual confounding cannot be disentangled in cross-sectional data