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"Coordinated regulation aimed at improving the appeal and satisfaction of ENDS available to smokers, while reducing the nicotine levels in combustible tobacco products to nonaddictive levels, may be necessary for ENDS to have a meaningful role in reducing the staggering public health burden of smoking." The authors noted that limitations of the study included having a limited ability to draw causal inferences from the observational design and a lack of biochemical verification of quitting smoking or ENDS use

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So instead of jumping up and down and complaining that their product is faulty, I went away resigned to having to smoke for the rest of my life." Indirect NRT Induced Deaths And therein lies NRT's deadly rub, that Neil, Helen and millions of other NRT quitters failed after having tried the very best that science had to offer