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This reduction was not seen in the two tobacco condensed aerosols or the other menthol condensed aerosol, potentially indicating that interaction of menthol flavoring chemicals with other chemicals such as carvone (terpenoid) can increase cytotoxicity ( Neuronal stem cells (NSCs) treated with either e-liquids or aerosols in cell culture media of either tobacco or menthol flavors (1%) showed a significant increase in total autophagosome area compared to the control at both 4- and 24-h time points

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