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Other factors that may increase the risk of oral cancer include: Gastroesophageal reflux disease (GERD) Previous radiation therapy to the head, neck, or both Exposure to certain chemicals, especially asbestos, sulphuric acid, and formaldehyde Having a long-term injury or chronic trauma, such as from rough teeth Drinking very hot mate tea, which is common in South America Eating a healthy diet with plenty of fresh fruits and vegetables may reduce the risk of the disease

Public Health 27 , 5662 (1999)

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Levels of nicotine in these products can vary from about 3 milligrams per packet up to 12 milligrams, and we know kids are sometimes doubling up with these, Halpern-Felsher said, putting them at risk of nicotine poisoning