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The systematic review conducted by Livingstone-Banks et al.,15 which was assigned a high AMSTAR2 rating, included five RCTs that met the PICO-SD criteria.20, 44, 58, 59, 60 Participants of the selected studies included general adult smokers (n = 3), smokers with medical or psychiatric conditions (n = 1), and methadone-treated smokers (n = 1)

In conclusion, MIR155HG participates in the apoptosis of CSE-induced HPMECs by regulating the miRNA-218-5p and BRD4 axis