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IQOS is a big success in Japan, where Wan reports it has "grabbed 10 percent of Japan's tobacco market -- a feat that has investors salivating over its U.S

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A 2014 study by the CDC revealed a significant uptick in nicotine vape pen-related calls to poison control centers the number of calls increased from one per month in September 2010 to 215 per month in February 2014, while the number of calls involving cigarettes remained steady over that time