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Although some toxic substances such as tar and suspended particles are reduced to a certain extent, most e-cigarettes are still as addictive as nicotine
The additional mucocutaneous features, including abnormal skin texture, easy bruising, hernias, piezogenic papules, light blue sclerae, uvular abnormalities, striae distensae/rubrae, keratosis pilaris/hyperkeratosis of extensor surfaces, absent/short lingual frenulum, resistance to local anesthetic drugs, and gingival inflammation/recession, are almost all shared not only with hEDS but also with other EDS subtypes and HCTDs [28, 29]
However, on May 9th, 2016, the FDA introduced new rules that extend their regulatory authority to now include Electronic Nicotine Delivery Systems (ENDS) which encompass e-cigarettes and similar devices