cigarette paper scars eds Are these “cigarette scars”? : r/eds Vascular Bleeding Disorders - Ask

Specifically, nicotine and its primary metabolite cotinine are metabolized by the uridine 5-diphospho-glucuronosyltransferase (UGT) superfamily enzymes: specifically UGT2B10 for nicotine and cotinine, and UGT2B7, UGT2B15, and UGT2B17 are responsible for metabolizing androgens

10.5mg of nicotine per day is akin to what a moderate smoker might get from cigarettes

Whole cigarettes (3 cigarettes from 3 different packages of the same variety) were extracted and analyzed in triplicate for the major commercial sensory cooling agents (menthol, WS-3, WS-23, WS-12, Frescolat MGA, Frescolat ML, Frescolat X-cool) by gas chromatography - mass spectrometry following published protocols (Supplementary file) 3

Endothelial dysfunction is an early warning sign of cardiovascular conditions like hypertension and atherosclerosis