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Jessica Yingst, assistant professor of public health sciences and Penn State Cancer Institute researcher, and colleagues at the Penn State Center for Research on Tobacco and Health study e-cigarettes and whether they can help nicotine users stop smoking or reduce their exposure to harmful toxicants found in cigarettes

Laryngeal cancer More common in men Strongly linked to tobacco and alcohol use Early diagnosis improves outcomes Radiotherapy, surgery and chemotherapy are the main treatments If the cancer is advanced, the patient may have to have surgery to remove part or all of the larynx These patients will no longer be able to speak or breathe in the usual way They will breathe through a permanent hole in their neck (stoma) and will need additional treatment to help restore their voice This may include a throat implant or an electrical device you hold against your throat to produce sound Source: NHS Choices, external One of the study authors, Prof Willie Hamilton, was the clinical lead for the current guidelines from The National Institute for Health and Care Excellence (NICE)

[136] Propylene glycol and glycerin typically comprise 95%, with the remaining 5% combining flavorings, nicotine, and other additives