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In summary, we believe the totality of the scientific evidence, coupled with our commitment to robust product quality, stewardship, engineering and manufacturing standards, as well as the implementation of effective youth access prevention programmes, convincingly demonstrates that our nicotine pouch products are potentially an effective THR tool beneficial to population-level health

This boundedness has material effects

For instance, we have reported that cigarette smoke, but not the aerosol of a heated tobacco product, caused the discoloration of dental resin composites used for fillings as well as human dentin and enamel [75]

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