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Cotinine is the principal (7080%) product of nicotine metabolization and is used as a biomarker in smokers, second-hand smokers, and children exposed to smoke (detectable in blood, urine, saliva, hair, and nail) [66, 67]

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Many cancers, such as breast cancer, that were once a death sentence are now treatable, yet lung cancer survival rates remain below 20 percent

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