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From the literature, parental reports of household passive smoke exposure have been found to be potentially biased for some reasons, including under-reporting of household smoking status and underestimation of exposure outside the household 33 , which taken together could have contributed to an underestimation of the extent of passive tobacco smoke exposure and could have led to the observed discrepancy in this study

About 30% of these loci are shared with UC, and about 50% of them are also shared with at least another immune-mediated disease (34)

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