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Availability of data and materials Data from the Heinz-Nixdorf Recall study are not publicly available, but can be obtained by filling a request for data use and explaining the aim of the planned analyses ( Abbreviations 3OH: Trans-3-hydroxy CPD: Cigarettes per day HNR: Heinz-Nixdorf Recall Study IQR: Interquartile range ISCO: International Standard Classification of Occupations ISEI: International Socio-Economic Index of occupational status R 2 : R-square SES: Socioeconomic status References Van der Heyden JHA, Schaap MM, Kunst AE, Esnaola S, Borrell C, Cox B, et al

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Heated tobacco product: Creates a vapor rather than smoke as the tobacco is not combusted but only heated