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Psychoneuroendocrinology 140 , 105715 (2022)

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However, she challenges the idea that GLP-1s alone cause this: It does not cause muscle wastingThat is the low-calorie diet that folks end up on when their appetites are crushed out by too high a dose. If you keep a lower dose and ensure people maintain a regular appetite so they can get enough calories and enough protein on board, you could potentially mitigate this side effect, she says