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Quick Answer: Topical GHK-Cu has no known interaction with semaglutide, tirzepatide, or other GLP-1 agonists The result for some patients is loose skin, especially in areas where significant subcutaneous fat was lost

37 , TPS1114TPS1114 (2019)

The biological activity of GHK-Cu fundamentally depends on its sophisticated copper coordination chemistry, which enables safe and efficient cellular copper delivery while avoiding the toxicity associated with free copper ions

A pragmatic monitoring approach checking total testosterone, free testosterone, SHBG, and haematocrit at baseline and at 36 months following any significant change in either treatment is advisable