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Q4. Is ALCAR safe for long-term use

Doi: Stagni F, Giacomini A, Emili M, Trazzi S, Guidi S, Sassi M, Ciani E, Rimondini R, Bartesaghi R (2016) Short- and Long-Term Effects of Neonatal Pharmacotherapy with Epigallocatechin-3-Gallate on Hippocampal Development in the Ts65Dn Mouse Model of Down Syndrome

2.8 Molecular docking The 3D structure for GHK-Cu was retrieved from PubChem and converted into mol2 format with Open Babel 3.1.1

Result: an 83-amino-acid peptide, 9111 Da molecular mass, preserved native disulfide bridges, IGF-1R affinity maintained at 0.5-1 nM, IGFBP affinity reduced 100-1000 fold, plasma half-life multiplied by 10 to 50 depending on models