Over time, this slowdown can create an environment conducive to certain microbes that thrive in stagnation, like methane-producers or those that might predispose to SIBO
For a side-by-side comparison of how semaglutide stacks up against the other major GLP-1 option, our semaglutide vs tirzepatide side effects guide compares the safety profiles in detail
Which should you choose
Ozempic label, AccessFDA Gastrointestinal adverse events associated with semaglutide: A pharmacovigilance study based on FDA adverse event reporting system, Frontiers in Public Health (2022) Gastrointestinal tolerability of onceweekly semaglutide 2.4 mg in adults with overweight or obesity, and the relationship between gastrointestinal adverse events and weight loss, Diabetes, Obesity, and Metabolism (2021) Risk of gastrointestinal adverse events associated with glucagon-like peptide-1 receptor agonists for weight loss, JAMA Network (2023) Constipation, Penn State College Medicine Foods for constipation, Johns Hopkins Medicine Exercise therapy in patients with constipation: A systematic review and meta-analysis of randomized controlled trials, Scandinavian Journal of Gastroenterology (2019) Bowel retraining, National Library of Medicine (2022) Concerned about constipation