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This is evidenced by reduced expression of ferroptosis-inhibiting genes such as GPX4 and SLC7A11, along with increased lipid peroxidation and iron accumulation in osteoarthritic chondrocytes from both the TMJ and the knee

Medically reviewed by Alan Lucks | MD , Alan Lucks MDPC Private Practice - New York on December 2nd, 2025

A count of blood cells in a patient with kidney disease may reveal reduced numbers of red blood cells (anemia) due to decreases in production of the hormone erythropoietin or may show blood concentration/dehydration due to the kidneys inability to prevent water loss (Ferri 2014a)